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Open Access Publications from the University of California
Cover page of Deep Learning Models to Attenuate CochlearImplant Artifacts in Pediatric Cortical AuditoryEvoked Potentials

Deep Learning Models to Attenuate CochlearImplant Artifacts in Pediatric Cortical AuditoryEvoked Potentials

(2024)

To develop a deep machine learning model that attenuates CI artifacts from EEG CAEPs. These CAEPs will more faithfully represent auditory cortex signals as compared with current denoising methodologies.

Cover page of The Impact of Recurrence or Presence of a New Malignancy on Tracheoesophageal Puncture Device Failure

The Impact of Recurrence or Presence of a New Malignancy on Tracheoesophageal Puncture Device Failure

(2024)

In the United States there are approximately 67,000 cases of Head and Neck Cancer annually and 15,400 deaths. The NIH estimates that in 2023 approximately 12, 380 new cases of laryngeal cancer, were diagnosed which has a 61.6% 5-year relative survival rate.The total laryngectomy is a surgical procedure that removes all of the laryngeal structures and sections of the upper trachea. Tracheoesophageal speech is considered the gold standard for voice rehabilitation following total laryngectomy. Tracheoesophageal speech utilizes a voice prosthesis (VP) that is inserted through a puncture in the common wall separating the trachea from the esophagus. The current literature has established that many factors that can impact a VP lifespan. In patients with advanced laryngeal cancer (T4a), up to 10% of patients can develop a recurrence, while less severe cases can result in up to 25% of recurrence. However, there is limited information on how the development of a secondary malignancy or recurrence can impact VP device failures or their lifespan. Therefore, understanding the factors that may influence TEP device failures particularly in the context of cancer recurrence or new malignancies is essential in the management of patients.

Cover page of Correlating the Neuro-ophthalmic Features in IIH with sCSF Leak

Correlating the Neuro-ophthalmic Features in IIH with sCSF Leak

(2023)

A spontaneous cerebrospinal fluid (CSF) leak occurs when the CSF egresses from the subarachnoid space of teh anterior or middle cranial fossa into the surrounding sinonasal or middle ear cavities through a dehiscence of the lamia dorsa.

Cover page of Fluoroscopic Swallow Study Predictors of Tracheoesophageal Puncture Voice Quality

Fluoroscopic Swallow Study Predictors of Tracheoesophageal Puncture Voice Quality

(2023)

Tracheoesophageal puncture (TEP) is the gold standard for voice rehabilitation after total laryngectomy (TL). TEP voicing can be challenging & unpredictable. The dynamicswallow study is a fluoroscopic swallow study part of standard clinical care prior to TEP placement. The study aimed to determine which objective dynamic swallow study (DSS) parameters predict improved voice outcomes in patients who have TEP placement.

Cover page of Low Income Areas Predict T Stage in Patients with Head and Neck Cancer

Low Income Areas Predict T Stage in Patients with Head and Neck Cancer

(2023)

A strong predictor of mortality in patients with head and neck cancer (HNC) is the stage of tumor at time of diagnosis. Studies suggest that income level is associated with poor putcomes in HNC patients.

Cover page of Factors influencing number of posttreatment visits following major head and neck oncologic surgery in the elderly

Factors influencing number of posttreatment visits following major head and neck oncologic surgery in the elderly

(2022)

Often, patients that present with head and neck squamous cell carcinoma (HNSCC) are in the seventh decade of life. The incidence of newly diagnosed HNSCC in the elderly is expected to increase by more than 60% by the year 2030. Optimizing postoperative care is vital for patients as they recover from major head and neck surgery to avoid complications, minimize hospital readmissions, decrease healthcare expenditure, and to surveil for recurrence. The aim of this study is to identify patient factors associated with an increased number of posttreatment visits in the first year after major head and neck oncologic surgery in the elderly.

Cover page of Treatment Outcomes with Conservative Management of Frontal Sinus Outflow Tract Fractures

Treatment Outcomes with Conservative Management of Frontal Sinus Outflow Tract Fractures

(2021)

Frontal sinus fractures represent approximately 10-15% of maxillofacial fractures and are generally a result of high-speed motor vehicle accidents, assaults, or sporting injuries1. Historic treatment options have included: observation, open reduction and internal fixation, obliteration, and cranialization. Frontal sinus fractures often occur with involvement of the frontal sinus outflow tract (FSOT) which has been treated aggressively to prevent complications including CSF leak, sinusitis, mucocele, meningitis, or brain abscess. To avoid the possibility of these complications, immediate surgical treatment of FSOT fractures has been a standard practice. However, early surgical intervention has an intrinsic morbidity, and through technologic and endoscopic advances, conservative management (i.e. observation) of FSOT fractures has become more common as well as a more viable option to treat the described long-term complications.

Cover page of Early Tracheostomy Management Varies Across Specialties

Early Tracheostomy Management Varies Across Specialties

(2021)

Tracheotomy is a common procedure which is uniquely performed by numerous specialties to manage the airway both acutely and chronically. There is limited consensus regarding tracheotomy procedure and tracheostomy tube management. The American Academy of Otolaryngology – Head & Neck Surgery has proposed best practices based on available evidence and expert consensus.

Cover page of Evaluating the Number of Pathologic Lymph Nodes In Oral Cavity Cancer

Evaluating the Number of Pathologic Lymph Nodes In Oral Cavity Cancer

(2021)

The epidemiology of head and neck squamous cell carcinoma (HNSCC) has been shifting with an increase in incidence of HPV-associated oropharyngeal HNSCC, which behaves less aggressively than HPV-negative HNSCC. This has prompted a paradigm shift in the newly released 8th edition American Joint Committee on Cancer (AJCC) staging guidelines for HPV-associated HNSCC pathologic nodal classification (counting positive lymph nodes), while HPV-negative HNSCC nodal staging has been largely unchanged from the 7th edition. This study aims to evaluate whether the pathologic number of lymph nodes is associated with oncologic outcomes in patients diagnosed with oral cavity HNSCC.

Cover page of Factors influencing healthcare utilization following major head and neck oncologic surgery in the elderly

Factors influencing healthcare utilization following major head and neck oncologic surgery in the elderly

(2021)

Often, patients that present with head and neck squamous cell carcinoma (HNSCC) are in the seventh decade of life with various comorbidities that are linked to heavy tobacco and alcohol abuse. The incidence of newly diagnosed HNSCC in the elderly is expected to increase by more than 60% by the year 2030. Optimizing postoperative care is vital for patients as they recover from major head and neck surgery to avoid complications, minimize hospital readmissions, and decrease healthcare expenditure. To our knowledge, there are no studies that investigate healthcare utilization in the elderly after major head and neck surgery. The aim of this study is to identify patient factors associated with increased postoperative healthcare use in the first year after surgery.