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Trajectory Of Project Baby Bear Rapid Genome Sequencing Project: A Review of Long-Term Follow Up at a Single Center

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Abstract

Project Baby Bear was a prospective quality improvement project which demonstrated the clinical utility and economic impact of ultrarapid or rapid whole genome sequencing (rWGS) in neonatal and pediatric intensive care units for Medi-Cal beneficiaries. This study found that rWGS provided a diagnosis for 40% of the patients and changed medical care for 32% of them. However, there is limited information on the long-term clinical outcomes and follow up of these individuals.

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