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Pathologic Hyperfibrinolysis Associated with Amyloidosis: Clinical Response to Epsilon Amino Caproic Acid

Published Web Location

https://doi.org/10.1093/ajcp/81.3.382
Abstract

Severe bleeding diathesis was the presenting problem in a patient with systemic amyloidosis characterized by generalized amyloid adenopathy. Epsilon amino caproic acid effectively reversed the fibrinolytic state with improvement of bleeding tendency and reduction of lymphadenopathy. The possible relationship and mechanisms of fibrinolysis are discussed.

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