Chabala, Chishala; Jacobs, Tom; Moraleda, Cinta; Ndaferankhande, John; Mumbiro, Vivian; Passanduca, Alfeu; Namuziya, Natasha; Nalwanga, Damalie; Musiime, Victor; Ballesteros, Alvaro; Domínguez-Rodríguez, Sara; Chitsamatanga, Moses; Cassia, Uneisse; Nduna, Bwendo; Bramugy, Justina; Sacarlal, Jahit; Madrid, Lola; Nathoo, Kusum; Colbers, Angela; Burger, David; Mulenga, Veronica; Buck, William; Mujuru, Hilda; Te Brake, Lindsey; Rojo, Pablo; Tagarro, Alfredo; Aarnoutse, Rob

doi:10.1093/jpids/piad088

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First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia.

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https://doi.org/10.1093/jpids/piad088

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Abstract

Optimal antituberculosis therapy is essential for favorable clinical outcomes. Peak plasma concentrations of first-line antituberculosis drugs in infants with living HIV receiving WHO-recommended dosing were low compared with reference values for adults, supporting studies on increased doses of first-line TB drugs in infants.

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First-Line Antituberculosis Drug Concentrations in Infants With HIV and a History of Recent Admission With Severe Pneumonia.

Published Web Location