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Open Access Publications from the University of California

Developing a Pediatric CAR T-cell Comorbidity Index: Evaluationof Pre-existing Models in Pediatric B-ALL Patients

Abstract

1. Test existing adult-validated predictive models of CAR associatedtoxicities in pediatric patients with B-ALL including the M-EASIX and CAR-HEMATOTOX model.

2. To determine if the M-EASIX and CAR-HEMATOTOX model can predict post-CAR outcomes including:• CRS and CRS Maximum Grade• ICANS and ICANS Maximum Grade

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