UC Irvine

In this study, we have developed an acoustic radiation force orthogonal excitation optical coherence elastography (ARFOE-OCE) method for the visualization of the shear wave and the calculation of the shear modulus based on the OCT Doppler variance method. The vibration perpendicular to the OCT detection direction is induced by the remote acoustic radiation force (ARF) and the shear wave propagating along the OCT beam is visualized by the OCT M-scan. The homogeneous agar phantom and two-layer agar phantom are measured using the ARFOE-OCE system. The results show that the ARFOE-OCE system has the ability to measure the shear modulus beyond the OCT imaging depth. The OCT Doppler variance method, instead of the OCT Doppler phase method, is used for vibration detection without the need of high phase stability and phase wrapping correction. An M-scan instead of the B-scan for the visualization of the shear wave also simplifies the data processing.