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Mohs micrographic surgery versus wide local excision for the treatment of atypical fibroxanthoma: a retrospective cohort study
Abstract
Atypical fibroxanthoma (AFX) is a rare pleomorphic, spindle cell neoplasm that typically presents as a solitary pink/red papule on the head or neck in elderlyindividuals.
Although they rarely metastasize, it is not uncommon for these tumors to locally recur, highlighting the importance of complete removal with negative surgical margins.
Current treatment guidelines recommend Mohs micrographic surgery (MMS) or wide local excision (WLE), yet MMS is generally preferred in clinical practice based on the limited data supporting superior recurrence rates.
However, there are very few studies that have compared these two surgical modalities, and some did not find meaningful differences in the rates of recurrence.
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