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Location, Location, Location: Transcriptional Control of Astrocyte Heterogeneity
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https://doi.org/10.1016/j.it.2020.07.011Abstract
Huang et al. have found that deletion of astrocyte lineage-specifying transcription factor NFIA from mature astrocytes alters astrocyte morphology, molecular identity, and synaptic-support capacity in a region-specific manner. We discuss the implications of these findings in light of emerging roles for astrocytes in immune cell crosstalk.
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