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Strategies for Network GWAS Evaluated Using Classroom Crowd Science.
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https://doi.org/10.1016/j.cels.2019.03.013Abstract
Biological networks can substantially boost power to identify disease genes in genome-wide association studies. To explore different network GWAS methods, we challenged students of a UC San Diego graduate level bioinformatics course, Network Biology and Biomedicine, to explore and improve such algorithms during a four-week-long classroom competition. Here, we report the many creative solutions and share our experiences in conducting classroom crowd science as both a research and pedagogical tool.
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