- Main
Skeletal muscle adiposity and outcomes in candidates for lung transplantation: a lung transplant body composition cohort study.
- Anderson, Michaela R;
- Easthausen, Imaani;
- Gallagher, Grace;
- Udupa, Jayaram;
- Tong, Yubing;
- Torigian, Drew;
- Diamond, Joshua Matthew;
- Porteous, Mary Katherine;
- Palmer, Scott M;
- Snyder, Laurie D;
- Benvenuto, Luke;
- Aversa, Meghan;
- Arcasoy, Selim;
- Greenland, John R;
- Hays, Steven R;
- Kukreja, Jasleen;
- Cantu, Edward;
- Kim, John Shinn;
- Gallagher, Dympna;
- Baldwin, Matthew R;
- Barr, R Graham;
- Lederer, David J;
- Christie, Jason D;
- Singer, Jonathan Paul
- et al.
Published Web Location
https://doi.org/10.1136/thoraxjnl-2019-214461Abstract
CT measurement of body composition may improve lung transplant candidate selection. We assessed whether skeletal muscle adipose deposition on abdominal and thigh CT scans was associated with 6 min walk distance (6MWD) and wait-list survival in lung transplant candidates. Each ½-SD decrease in abdominal muscle attenuation (indicating greater lipid content) was associated with 14 m decrease in 6MWD (95% CI -20 to -8) and 20% increased risk of death or delisting (95% CI 10% to 40%). Each ½-standard deviation decrease in thigh muscle attenuation was associated with 15 m decrease in 6MWD (95% CI -21 to -10). CT imaging may improve candidate risk stratification.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.
Main Content
Enter the password to open this PDF file:
-
-
-
-
-
-
-
-
-
-
-
-
-
-