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Changes in Body Mass Index with Longer-term Integrase Inhibitor Use: A Longitudinal Analysis of Data from the Randomized Trial to Prevent Vascular Events in Human Immunodeficiency Virus (REPRIEVE).
- Kileel, Emma;
- Malvestutto, Carlos;
- Lo, Janet;
- Fitch, Kathleen;
- Fichtenbaum, Carl;
- Aberg, Judith;
- Zanni, Markella;
- Martinez, Esteban;
- Okeke, Nwora;
- Kumar, Princy;
- Joao, Esau;
- Bares, Sara;
- Berrner, Daniel;
- Smieja, Marek;
- Roa, Jhoanna;
- McCallum, Sara;
- Douglas, Pamela;
- Ribaudo, Heather;
- Grinspoon, Steven
- et al.
Published Web Location
https://doi.org/10.1093/cid/ciad107Abstract
Over 2-years of follow-up, integrase strand transfer inhibitor (INSTI)-use was associated with weight gain among those on an INSTI <2 years at entry (+0.27 kg/m2/year; 95% confidence interval [CI], .22 to .33 vs +0.17 kg/m2/year; 95% CI, .12 to .23; P = .01), but not those on an entry INSTI >2 years.
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