Mabray, Marc C; Behr, Spencer C; Naeger, David M; Flavell, Robert R; Glastonbury, Christine M

doi:10.1016/j.clinimag.2015.07.005

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Predictors of pathologic outcome of focal FDG uptake in the parotid gland identified on whole-body FDG PET imaging

2015

Published Web Location

https://doi.org/10.1016/j.clinimag.2015.07.005

Abstract

Purpose

The purpose was to test whether patient's primary malignancy type and presence of F-18-fluorodeoxyglucose (FDG)-avid cervical lymph node(s) are predictors of pathologic outcome of incidental focal FDG-avid parotid lesions.

Basic procedures

A retrospective cohort study of pathologically proven incidental cases was performed.

Main findings

Focal parotid FDG uptake in the setting of head and neck cancer/melanoma [odds ratio (OR)=24.6, P<.01], lymphoma (OR=7.2, P=.02), or FDG-avid cervical lymph node(s) (OR=3.6, P=.07) has a higher odds of representing metastases. No malignant primary parotid tumors were incidentally discovered.

Principal conclusions

In patients with head and neck cancer/melanoma, lymphoma, or FDG-avid cervical lymph node(s), there were higher odds that focal parotid FDG uptake was a metastasis.

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