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Targeted Isotretinoin in Neuroblastoma: Kinetics, Genetics, or Absorption
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https://doi.org/10.1158/1078-0432.ccr-12-3313Abstract
Isotretinoin (13-cis-retinoic acid; 13-cisRA) has been shown to significantly improve survival for children with high-risk neuroblastoma. Pharmacokinetics of isotretinoin may be negatively affected by the mode of drug administration and the dosing formula.
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