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Purloined Mechanisms of Bacterial Immunity Can Cure Muscular Dystrophy
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https://doi.org/10.1016/j.cmet.2014.11.011Abstract
Myriad strategies have been explored to compensate for the lack of dystrophin or to skip mutations that cause the lethal disease Duchenne muscular dystrophy (DMD). A new study shows that gene editing strategies used by bacteria can be applied in zygotes of a mouse model of DMD to correct the genetic defect that causes muscular dystrophy (Long et al., 2014).
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