UC Davis

Purpose of Review: This article aims to discuss the structure and function of fascial systems and the potential role in myofascial pain syndromes. Recent Findings: New terminology differentiates anatomic structure (fascia) and function (fascial system), improving the conceptual framework and communication. Fascia has been shown to be innervated and biologically active and may have roles in nociception, proprioception, and myofascial force transmission. A number of factors may modify the function of fascial tissues through altering stiffness. A new cell type, “fasciacytes,” produces hyaluronic acid, a molecule critical to fascial lubrication. Fascial contribution to myofascial pain syndromes remains unclear, though plausible mechanisms connect them, and direct evidence of fascia-mediated pain exists. Current evidence is limited to support fascia-directed therapies for myofascial pain syndromes. Summary: Developing evidence implicates fascial tissue in musculoskeletal function and myofascial pain syndromes. Further investigation into fascial physiology and pathophysiology is needed to translate this knowledge into clinical care.