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Micro(RNA) Managing by mTORC1
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https://doi.org/10.1016/j.molcel.2015.02.006Abstract
In this issue of Molecular Cell, Ye et al. (2015) demonstrate that mTORC1 globally regulates miRNA biogenesis under nutrient-rich conditions via the E3 ubiquitin ligase Mdm2, which promotes Drosha degradation.
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