BACKGROUND: This study investigated whether subjective unrest-related distress was associated with probable depression during and after the 2019 anti-ELAB movement in Hong Kong. METHODS: Population-representative data were collected from 7157 Hong Kong Chinese in four cross-sectional surveys (July 2019-July 2020). Logistic regression examined the association between subjective unrest-related distress and probable depression (PHQ-9 ⩾ 10), stratified by the number of conflicts/protests across the four timepoints. RESULTS: Unrest-related distress was positively associated with probable depression across different numbers of conflicts/protests. CONCLUSION: Unrest-related distress is a core indicator of probable depression. Public health interventions should target at resolving the distress during seemingly peaceful period after unrest.