The fundamental legal, normative, and politico-economic assumptions underpinning both competition law and administrative governance are in a period of considerable flux (Harris and Varellas 2020, 3; Britton-Purdy et al. 2020, 1801-02; Khan 2019; Rahman 2018). Past calls for a renewed economic analysis of law are striking a chord with present scholars. In this issue of the Journal of Law and Political Economy, we commence a specially edited series of articles focused on the value, shortcomings, and potential improvement of quantitative analysis in competition law and regulatory decision-making. This multi-year project aims to provide guidance and insight to advocates, judges, and regulators on the proper nature and scope of quantitative methods in several important areas of law and policy.