We report the observation of a quasi-coherent fluctuation (QCF) by the Doppler backscattering system in the scrape-off layer (SOL) region of the DIII-D tokamak. This QCF is observed in high power, high performance hybrid plasmas with near double-null divertor shape during the electron cyclotron heating period. This mode is correlated with a steepened SOL density profile, and leads to significantly elevated particle and heat fluxes between edge localized modes. The SOL QCF is a long-wavelength ion-scale fluctuation (kθ ρs ≈ 0.2-0.4 and kr ρs ≈ 0.03), and propagates in the ion diamagnetic direction in the plasma frame. Its radial expanse is about 1.5-2 cm, well beyond the typical width of heat flux λ q on DIII-D. Also, the SOL QCF does not show any clear dependence on the effective SOL collisionality, and thus may raise issues on the control of plasma-material interactions in low collisionality plasmas in which the blob-induced transport is reduced. A linear simulation using BOUT++ with a five-field reduced model is performed and compared with experimental observations. In simulation results, an interchange-like density perturbation can be driven by the SOL density gradient, and its peak location and the radial width of the density perturbation are in agreement with the experimental observations.