MOTIVATION: Network biology is a dominant player in todays multi-omics era. Therefore, the need for visualization tools which can efficiently cope with intra-network heterogeneity emerges. RESULTS: NORMA-2.0 is a web application which uses efficient layouts to group together areas of interest in a network. In this version, NORMA-2.0 utilizes three different strategies to make such groupings as distinct as possible while it preserves all of the properties from its first version where one can handle multiple networks and annotation files simultaneously. AVAILABILITY AND IMPLEMENTATION: The web resource is available at http://norma.pavlopouloslab.info/. The source code is freely available at https://github.com/PavlopoulosLab/NORMA.