Department of Cellular & Molecular Medicine - Open Access Policy Deposits

Parent: School of Medicine

eScholarship stats: Breakdown by Item for December, 2024 through March, 2025

ItemTitleTotal requestsDownloadView-only%Dnld
0d951135Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature.16501650.0%
9044v022Brain organoids, consciousness, ethics and moral status1615510634.2%
2bt9p0zzThe RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis14931462.0%
70c3m48jSpindle assembly checkpoint activation and silencing at kinetochores.124368829.0%
59b4x253Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML1231311010.6%
232927v1SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2117338428.2%
8j35h8jnArchitecture and self‐assembly of the SARS‐CoV‐2 nucleocapsid protein969879.4%
219597nnZika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis958878.4%
85j9m77hControl of bacterial immune signaling by a WYL domain transcription factor93118211.8%
1m706149Reversing a model of Parkinson’s disease with in situ converted nigral neurons874834.6%
0tt0x846Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management833803.6%
3710176wGap junctions: historical discoveries and new findings in the Caenorhabditis elegans nervous system837768.4%
7b11m3h2Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals812792.5%
8s13b2f8Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development801791.3%
2231q4mbParkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration792772.5%
404994bxToxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss792772.5%
50w2z43fTranscriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer795746.3%
0r65r9b9Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells7586710.7%
3vq7746fGIV/Girdin and Exo70 Collaboratively Regulate the Mammalian Polarized Exocytic Machinery755706.7%
8jj6580kSialoglycan-binding patterns of bacterial AB<sub>5</sub> toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits.754715.3%
9s9286njIdentification of H3K4me1-associated proteins at mammalian enhancers750750.0%
4rs831wxExcitatory motor neurons are local oscillators for backward locomotion715667.0%
1799t2f2Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore.651641.5%
2mf8p4v3RTN3L and CALCOCO1 function in parallel to maintain proteostasis in the endoplasmic reticulum.65224333.8%
44q19509C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation631621.6%
3pv76061E-cigarettes compromise the gut barrier and trigger inflammation5594616.4%
5kd0v4kqLarge-scale tethered function assays identify factors that regulate mRNA stability and translation50272354.0%
0xm8q84fCircular ecDNA promotes accessible chromatin and high oncogene expression474438.5%
9b82739rUncovering novel mutational signatures by de novo extraction with SigProfilerExtractor4664013.0%
38q405h0Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities45252055.6%
0853h6t4DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages4473715.9%
1t76v633Modeling colorectal cancers using multidimensional organoids44202445.5%
551458jjAPOE4/4 is linked to damaging lipid droplets in Alzheimers disease&nbsp;microglia.44172738.6%
1mf8f8xbIdentification of phagocytosis regulators using magnetic genome-wide CRISPR screens430430.0%
1zt4w4dzThe Three-Dimensional Organization of Mammalian Genomes4383518.6%
4bc6c9wgExposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro4253711.9%
4qn8b3qfBlocking Zika virus vertical transmission424389.5%
0jb936p7Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies.413387.3%
2nz1949jA large-scale binding and functional map of human RNA-binding proteins41182343.9%
6z9096mfAn in&nbsp;vivo neuroimmune organoid model to study human microglia phenotypes.41132831.7%
8077v518Correction: Gene expression and chromatin conformation of microglia in virally suppressed people with HIV.413387.3%
9v02c4c4Control of cell proliferation by memories of mitosis.392375.1%
08r3t35wTumour predisposition and cancer syndromes as models to study gene-environment interactions.38122631.6%
0bw638xsArchitecture and self-assembly of the jumbo bacteriophage nuclear shell38142436.8%
5s47j042First Organoid Intelligence (OI) workshop to form an OI community383357.9%
10q5b97wRANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression37132435.1%
36t6t6t8A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome373348.1%
4bd0d5wsAn environment-dependent transcriptional network specifies human microglia identity37102727.0%
8vf9p8g0Diet-regulated production of PDGFcc by macrophages controls energy storage37112629.7%
8x30b7h0Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation37162143.2%

Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.