Department of Cellular & Molecular Medicine - Open Access Policy Deposits
Parent: School of Medicine
eScholarship stats: Breakdown by Item for September through December, 2024
Item | Title | Total requests | Download | View-only | %Dnld |
---|---|---|---|---|---|
9044v022 | Brain organoids, consciousness, ethics and moral status | 137 | 48 | 89 | 35.0% |
2bt9p0zz | The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis | 136 | 1 | 135 | 0.7% |
70c3m48j | Spindle assembly checkpoint activation and silencing at kinetochores. | 111 | 38 | 73 | 34.2% |
0tt0x846 | Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management | 108 | 2 | 106 | 1.9% |
232927v1 | SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 | 97 | 17 | 80 | 17.5% |
219597nn | Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis | 89 | 12 | 77 | 13.5% |
85j9m77h | Control of bacterial immune signaling by a WYL domain transcription factor | 85 | 11 | 74 | 12.9% |
8j35h8jn | Architecture and self‐assembly of the SARS‐CoV‐2 nucleocapsid protein | 81 | 7 | 74 | 8.6% |
1m706149 | Reversing a model of Parkinson’s disease with in situ converted nigral neurons | 80 | 6 | 74 | 7.5% |
404994bx | Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss | 79 | 3 | 76 | 3.8% |
3710176w | Gap junctions: historical discoveries and new findings in the Caenorhabditis elegans nervous system | 74 | 4 | 70 | 5.4% |
8jj6580k | Sialoglycan-binding patterns of bacterial AB<sub>5</sub> toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits. | 71 | 0 | 71 | 0.0% |
0r65r9b9 | Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells | 70 | 3 | 67 | 4.3% |
4rs831wx | Excitatory motor neurons are local oscillators for backward locomotion | 68 | 3 | 65 | 4.4% |
7b11m3h2 | Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals | 68 | 1 | 67 | 1.5% |
44q19509 | C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation | 67 | 5 | 62 | 7.5% |
8s13b2f8 | Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development | 67 | 0 | 67 | 0.0% |
3vq7746f | GIV/Girdin and Exo70 Collaboratively Regulate the Mammalian Polarized Exocytic Machinery | 66 | 4 | 62 | 6.1% |
9s9286nj | Identification of H3K4me1-associated proteins at mammalian enhancers | 66 | 2 | 64 | 3.0% |
2231q4mb | Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration | 63 | 2 | 61 | 3.2% |
50w2z43f | Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer | 61 | 0 | 61 | 0.0% |
6z9096mf | An in vivo neuroimmune organoid model to study human microglia phenotypes. | 53 | 14 | 39 | 26.4% |
3pv76061 | E-cigarettes compromise the gut barrier and trigger inflammation | 50 | 6 | 44 | 12.0% |
4bd0d5ws | An environment-dependent transcriptional network specifies human microglia identity | 43 | 21 | 22 | 48.8% |
5kd0v4kq | Large-scale tethered function assays identify factors that regulate mRNA stability and translation | 42 | 24 | 18 | 57.1% |
2pm3h6j9 | Human microglia maturation is underpinned by specific gene regulatory networks. | 40 | 10 | 30 | 25.0% |
0h227304 | The cytoplasmic dynein transport machinery and its many cargoes | 35 | 22 | 13 | 62.9% |
4bc6c9wg | Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro | 33 | 1 | 32 | 3.0% |
8fz9q8fw | Lipid-associated macrophages’ promotion of fibrosis resolution during MASH regression requires TREM2 | 32 | 0 | 32 | 0.0% |
7zm0x62m | Alteration of Neuropilin‑1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth | 31 | 6 | 25 | 19.4% |
2mf8p4v3 | RTN3L and CALCOCO1 function in parallel to maintain proteostasis in the endoplasmic reticulum. | 29 | 7 | 22 | 24.1% |
8x30b7h0 | Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation | 29 | 22 | 7 | 75.9% |
0xm8q84f | Circular ecDNA promotes accessible chromatin and high oncogene expression | 27 | 5 | 22 | 18.5% |
9ns984bk | Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes | 27 | 4 | 23 | 14.8% |
4m11z022 | Somatic mosaicism reveals clonal distributions of neocortical development | 26 | 3 | 23 | 11.5% |
6z35c13b | TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4. | 26 | 8 | 18 | 30.8% |
33s4f630 | Implementation of Practical Surface SARS-CoV-2 Surveillance in School Settings | 25 | 5 | 20 | 20.0% |
4rn7d07h | Joint profiling of histone modifications and transcriptome in single cells from mouse brain | 25 | 15 | 10 | 60.0% |
8077v518 | Correction: Gene expression and chromatin conformation of microglia in virally suppressed people with HIV. | 25 | 2 | 23 | 8.0% |
00g3j9wp | Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimers disease. | 24 | 6 | 18 | 25.0% |
266636nx | Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4. | 24 | 5 | 19 | 20.8% |
33p6091g | Autism risk in offspring can be assessed through quantification of male sperm mosaicism | 24 | 2 | 22 | 8.3% |
4np471k5 | Temporally distinct 3D multi-omic dynamics in the developing human brain | 24 | 0 | 24 | 0.0% |
8598b09m | HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells | 24 | 6 | 18 | 25.0% |
1rb9641n | Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for Age-Related Neuropathogenesis. | 23 | 4 | 19 | 17.4% |
6nt244k4 | Generation of ‘semi-guided’ cortical organoids with complex neural oscillations | 23 | 3 | 20 | 13.0% |
5qz4h5f8 | Nuclei isolation of multiple brain cell types for omics interrogation | 22 | 13 | 9 | 59.1% |
86h3m37p | SRPK1 acetylation modulates alternative splicing to regulate cisplatin resistance in breast cancer cells | 22 | 9 | 13 | 40.9% |
0pr3p7sm | Bacteria-Inspired Nanomedicine | 21 | 6 | 15 | 28.6% |
1q9817wd | Transcriptionally active HERV-H retrotransposons demarcate topologically associating domains in human pluripotent stem cells | 21 | 5 | 16 | 23.8% |
Note: Due to the evolving nature of web traffic, the data presented here should be considered approximate and subject to revision. Learn more.