Department of Molecular and Medical Pharmacology
Parent: UCLA
eScholarship stats: History by Item for November, 2024 through February, 2025
| Item | Title | Total requests | 2025-02 | 2025-01 | 2024-12 | 2024-11 |
|---|---|---|---|---|---|---|
| 1n83k1hm | The “cancer immunogram” | 348 | 72 | 82 | 80 | 114 |
| 54c114pc | Multivalent N‑Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing | 230 | 90 | 60 | 41 | 39 |
| 4xj2w70k | Chapter Five Advances in PET Detection of the Antitumor T Cell Response | 220 | 65 | 64 | 54 | 37 |
| 5st231s3 | Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy | 191 | 68 | 46 | 54 | 23 |
| 0bh4n1vq | Targeted agents and immunotherapies: optimizing outcomes in melanoma. | 140 | 31 | 34 | 39 | 36 |
| 9292w8n6 | Multiple early factors anticipate post-acute COVID-19 sequelae | 115 | 22 | 29 | 28 | 36 |
| 19k5q59f | The pentose phosphate pathway in health and disease. | 111 | 46 | 30 | 18 | 17 |
| 1wm4z4cd | Systematic transcriptome-wide meta-analysis across endocrine disrupting chemicals reveals shared and unique liver pathways, gene networks, and disease associations | 111 | 24 | 30 | 24 | 33 |
| 9623t7mm | Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence | 104 | 20 | 32 | 44 | 8 |
| 2t45m6gj | Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study. | 87 | 21 | 25 | 23 | 18 |
| 9nh2d4t3 | The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair | 85 | 25 | 29 | 14 | 17 |
| 1dc6s7xj | The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma. | 84 | 23 | 17 | 22 | 22 |
| 3vk9k174 | Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles | 84 | 24 | 27 | 20 | 13 |
| 61c3v6b7 | Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins | 84 | 23 | 22 | 23 | 16 |
| 6867n8kj | Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models. | 84 | 23 | 27 | 22 | 12 |
| 18p914db | Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy | 83 | 22 | 23 | 22 | 16 |
| 50n903xc | Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses | 83 | 17 | 23 | 24 | 19 |
| 8p963376 | Biglycan gene connects metabolic dysfunction with brain disorder. | 83 | 18 | 30 | 22 | 13 |
| 3bg4h9n7 | Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001 | 82 | 22 | 21 | 25 | 14 |
| 3gk1p7kf | PSMA PET validates higher rates of metastatic disease for European Association of Urology Biochemical Recurrence Risk Groups: an international multicenter study | 82 | 22 | 21 | 23 | 16 |
| 63q4v54c | β-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production | 82 | 24 | 20 | 20 | 18 |
| 1pc070cw | Identification and validation of genes affecting aortic lesions in mice | 81 | 14 | 31 | 21 | 15 |
| 7jm3422h | PD-1 blockade induces responses by inhibiting adaptive immune resistance | 80 | 18 | 29 | 22 | 11 |
| 9jm2w1xh | Gene editing: Towards the third generation of adoptive T-cell transfer therapies | 79 | 24 | 21 | 17 | 17 |
| 3k646152 | Utomilumab in Patients With Immune Checkpoint Inhibitor-Refractory Melanoma and Non-Small-Cell Lung Cancer | 78 | 19 | 21 | 19 | 19 |
| 21x3z6hr | Spartalizumab or placebo in combination with dabrafenib and trametinib in patients with BRAF V600-mutant melanoma: exploratory biomarker analyses from a randomized phase 3 trial (COMBI-i) | 77 | 23 | 21 | 24 | 9 |
| 3t8708z1 | Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes | 77 | 25 | 21 | 16 | 15 |
| 5410d0x6 | Relative contributions of sex hormones, sex chromosomes, and gonads to sex differences in tissue gene regulation | 77 | 24 | 22 | 18 | 13 |
| 0qv0707j | Mergeomics: a web server for identifying pathological pathways, networks, and key regulators via multidimensional data integration | 76 | 21 | 20 | 19 | 16 |
| 0tp1638w | Dynamic Changes in the Subgingival Microbiome and Their Potential for Diagnosis and Prognosis of Periodontitis | 75 | 22 | 18 | 15 | 20 |
| 5qm5q3nv | Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico | 75 | 24 | 15 | 19 | 17 |
| 38x6x4vz | Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids | 74 | 23 | 21 | 16 | 14 |
| 466365dq | Future perspectives in melanoma research: meeting report from the “Melanoma Bridge”: Napoli, December 3rd–6th 2014 | 74 | 19 | 19 | 23 | 13 |
| 5jv9f3s6 | Genome-Wide RNAi High-Throughput Screen Identifies Proteins Necessary for the AHR-Dependent Induction of CYP1A1 by 2,3,7,8-Tetrachlorodibenzo-p-dioxin | 74 | 19 | 21 | 19 | 15 |
| 04m512v0 | 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues | 73 | 20 | 22 | 17 | 14 |
| 668692jt | Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells | 73 | 21 | 22 | 16 | 14 |
| 9qd4738k | Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia | 73 | 23 | 22 | 14 | 14 |
| 03j4k0f6 | Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis | 72 | 17 | 20 | 22 | 13 |
| 6t49338z | The whole-genome landscape of medulloblastoma subtypes | 72 | 27 | 20 | 13 | 12 |
| 2gn1f3nr | Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013 | 71 | 20 | 18 | 22 | 11 |
| 9139f6vj | Click chemistry-mediated enrichment of circulating tumor cells and tumor-derived extracellular vesicles for dual liquid biopsy in differentiated thyroid cancer | 71 | 9 | 21 | 25 | 16 |
| 9h88g674 | Improved Leakage Correction for Single-Echo Dynamic Susceptibility Contrast Perfusion MRI Estimates of Relative Cerebral Blood Volume in High-Grade Gliomas by Accounting for Bidirectional Contrast Agent Exchange. | 71 | 18 | 24 | 17 | 12 |
| 5nv9f110 | Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression | 70 | 28 | 19 | 13 | 10 |
| 6dn6b8jq | Phase 3 multicenter randomized trial of PSMA PET/CT prior to definitive radiation therapy for unfavorable intermediate-risk or high-risk prostate cancer [PSMA dRT]: study protocol | 70 | 18 | 18 | 21 | 13 |
| 6v3011pd | Cancer immunotherapy using checkpoint blockade | 69 | 27 | 26 | 5 | 11 |
| 8v80b071 | A novel multi-reaction microdroplet platform for rapid radiochemistry optimization | 69 | 19 | 14 | 22 | 14 |
| 92m8q260 | Anti-programmed cell death protein-1/ligand-1 therapy in different cancers | 69 | 17 | 20 | 16 | 16 |
| 4kq37633 | Ionic-surfactant-mediated electro-dewetting for digital microfluidics. | 66 | 21 | 17 | 14 | 14 |
| 39f4d1hw | Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis | 65 | 15 | 16 | 16 | 18 |
| 46k1r1zp | 5-(2-[18 F]Fluoroethyl)-4-Methylthiazole Probe For Positron Emission Tomography Of The Central Nervous System | 65 | 15 | 19 | 21 | 10 |
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