Biological Systems & Engineering

eScholarship stats: History by Item for October, 2024 through January, 2025

Item	Title	Total requests	2025-01	2024-12	2024-11	2024-10
25s902m0	Microbial production of advanced biofuels	181	33	43	60	45
5n75t404	Pre-metastatic niches: organ-specific homes for metastases	171	69	27	35	40
91c7c0t1	Thirdhand smoke exposure promotes gastric tumor development in mouse and human	151	151
6r99w1b4	Complete biosynthesis of cannabinoids and their unnatural analogues in yeast	145	49	25	35	36
9d4221mc	De novo DNA synthesis using polymerase-nucleotide conjugates	143	32	23	42	46
44p4p26z	The impact of reducing signal acquisition specifications on neuronal spike sorting	114	35	35	15	29
9pm0x5mh	Machine learning for metabolic engineering: A review	110	31	25	23	31
0ms113jv	Engineered Production of Short-Chain Acyl-Coenzyme A Esters in Saccharomyces cerevisiae	107	35	24	21	27
77f5s184	The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice	99	26	20	24	29
4369p87c	Methane to bioproducts: unraveling the potential of methanotrophs for biomanufacturing	98	41	35	14	8
83w5k207	Can Multiple Ions in an Ionic Liquid Improve the Biomass Pretreatment Efficacy?	97	29	26	16	26
20q2b1g9	Overcoming the anaerobic hurdle in phenotypic microarrays: Generation and visualization of growth curve data for Desulfovibrio vulgaris Hildenborough	90	23	22	19	26
2s7057qf	Effects of Six Sequential Charged Particle Beams on Behavioral and Cognitive Performance in B6D2F1 Female and Male Mice	90	27	19	15	29
8x348203	An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys	90	23	22	19	26
2zw971kg	Metabolic engineering strategies for sesquiterpene production in microorganism	89	19	28	14	28
7cx5710p	1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life	88	30	14	19	25
2z5184j0	Comparing in planta accumulation with microbial routes to set targets for a cost-competitive bioeconomy	86	24	20	18	24
8694191z	A novel d-xylose isomerase from the gut of the wood feeding beetle Odontotaenius disjunctus efficiently expressed in Saccharomyces cerevisiae	85	17	23	17	28
9708r7c2	Age‐associated expression of p21and p53 during human wound healing	85	24	20	14	27
1072827g	Genome-wide identification of zero nucleotide recursive splicing in Drosophila	83	15	24	16	28
1q20v09z	Scalable and automated CRISPR-based strain engineering using droplet microfluidics	83	24	24	14	21
5tz463wq	Gene variants as risk factors for gastroschisis	83	27	25	14	17
4r13f621	Xylose induces cellulase production in Thermoascus aurantiacus	81	27	17	18	19
51g19549	Multiomics Data Collection, Visualization, and Utilization for Guiding Metabolic Engineering	81	20	25	17	19
44m5x08n	MACAW: An Accessible Tool for Molecular Embedding and Inverse Molecular Design	80	19	19	18	24
54h8z0j1	Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse	79	30	18	14	17
8kz6z32z	GLYCEROL PHOSPHATE SHUTTLE IN VIRUS-TRANSFORMED CELLS IN CULTURE	79	26	14	17	22
1tz4z0c4	Clinically applicable 53-Gene prognostic assay predicts chemotherapy benefit in gastric cancer: A multicenter study	78	19	18	14	27
1vn426h2	CUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to Erlotinib via transcriptional regulation of EGFR	78	17	23	18	20
48z2q5d9	Listeria monocytogenes requires cellular respiration for NAD+ regeneration and pathogenesis	78	29	17	13	19
6292x5hz	On the solution structure of kraft lignin in ethylene glycol and its implication for nanoparticle preparation	78	24	22	12	20
30f3d4hv	A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.	77	18	23	15	21
3tv5p90q	Parallel Integration and Chromosomal Expansion of Metabolic Pathways	77	24	16	16	21
1pw5w78x	From Mouse to Human: Cellular Morphometric Subtype Learned From Mouse Mammary Tumors Provides Prognostic Value in Human Breast Cancer	76	22	17	18	19
2779c624	Ensemble models of feedstock blend ratios to minimize supply chain risk in bio-based manufacturing	76	18	19	20	19
87h7j1t3	Verazine biosynthesis from simple sugars in engineered Saccharomyces cerevisiae	76	14	50	4	8
94j1p3cc	Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice	76	19	22	12	23
82k8597n	Exercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review	75	16	23	17	19
9sg0t125	iCEMIGE: Integration of CEll-morphometrics, MIcrobiome, and GEne biomarker signatures for risk stratification in breast cancers	74	23	21	10	20
4n6807hf	Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells.	73	20	20	17	16
669604tj	A bacterial metapopulation adapts locally to phage predation despite global dispersal	73	24	17	15	17
2jd3r4qd	Biofuels for a sustainable future	72	22	15	18	17
2vm495r2	A Novel DNA Repair Gene Signature for Immune Checkpoint Inhibitor-Based Therapy in Gastric Cancer	72	17	21	9	25
4c13952r	INHIBITION OF ADENOCARCINOMA TA3 ASCITES TUMOR GROWTH BY RIFAMYCIN DERIVATIVES	72	18	15	16	23
70c9t9s9	Systems-Level Properties of EGFR-RAS-ERK Signaling Amplify Local Signals to Generate Dynamic Gene Expression Heterogeneity	71	21	17	14	19
0s12j707	σ54-dependent regulome in Desulfovibrio vulgaris Hildenborough	69	17	21	13	18
6cr3k0v5	Droplet microfluidics for synthetic biology	69	20	19	14	16
6vg8d5d6	Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience	66	15	19	13	19
30v5j627	Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice	65	16	6	16	27
8r11g155	Evaluating the impact of biodiversity offsetting on native vegetation.	65	15	13	17	20

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