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High-resolution crystal structure of human protease-activated receptor 1
Published Web Location
http://europepmc.org/articles/PMC3531875?pdf=renderNo data is associated with this publication.
Abstract
Protease-activated receptor 1 (PAR1) is the prototypical member of a family of G-protein-coupled receptors that mediate cellular responses to thrombin and related proteases. Thrombin irreversibly activates PAR1 by cleaving the amino-terminal exodomain of t
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