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Pharmacological brake-release of mRNA translation enhances cognitive memory

Published Web Location

http://europepmc.org/articles/PMC3667625?pdf=render
No data is associated with this publication.
Abstract

Phosphorylation of the α-subunit of initiation factor 2 (eIF2) controls protein synthesis by a conserved mechanism. In metazoa, distinct stress conditions activate different eIF2α kinases (PERK, PKR, GCN2, and HRI) that converge on phosphorylating a unique

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