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Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

Published Web Location

http://europepmc.org/articles/PMC3531493?pdf=render
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Abstract

Cellular restriction factors help to defend humans against human immunodeficiency virus (HIV). HIV accessory proteins hijack at least three different Cullin-RING ubiquitin ligases, which must be activated by the small ubiquitin-like protein NEDD8, in order

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