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Pten loss in the bone marrow leads to G-CSF-mediated HSC mobilization
Published Web Location
http://europepmc.org/articles/PMC3804947?pdf=renderNo data is associated with this publication.
Abstract
The phosphatase and tumor suppressor PTEN inhibits the phosphoinositol-3-kinase (PI3K) signaling pathway and plays a key role in cell growth, proliferation, survival, and migration. Pten conditional deletion using MxCre or Scl-CreERT leads to splenomegaly
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