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FGF-23 Regulates CYP27B1 Transcription in the Kidney and in Extra-Renal Tissues
Published Web Location
http://europepmc.org/articles/PMC3760837?pdf=renderNo data is associated with this publication.
Abstract
The mitochondrial enzyme 25-hydroxyvitamin D 1α-hydroxylase, which is encoded by the CYP27B1 gene, converts 25OHD to the biological active form of vitamin D, 1,25-dihydroxyvitamin D (1,25(OH)2D). Renal 1α-hydroxylase activity is the principal determinant o
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