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Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG
Published Web Location
http://europepmc.org/articles/PMC4424347?pdf=renderNo data is associated with this publication.
Abstract
© 2015 by The American Society for Biochemistry and Molecular Biology, Inc.Neuromyelitis optica-immunoglobulin G (NMO-IgG) binds to aquaporin-4 (AQP4) water channels in the central nervous system leading to immune-mediated injury. We have previously demons
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