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PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis

Published Web Location

http://europepmc.org/articles/PMC3436829?pdf=render
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Abstract

Motivation: A current challenge in understanding cancer processes is to pinpoint which mutations influence the onset and progression of disease. Toward this goal, we describe a method called PARADIGMSHIFT that can predict whether a mutational event is neut

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