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Scholarly Works (1 results)

Article
Peer Reviewed

Depletion of murine fetal hematopoietic stem cells with c-Kit receptor and CD47 blockade improves neonatal engraftment

Witt, Russell G;
Wang, Bowen;
Nguyen, Quoc-Hung;
Eikani, Carlo;
Mattis, Aras N;
MacKenzie, Tippi C

UC San Francisco Previously Published Works (2018)

Fetal injection of antibodies against the c-Kit receptor and CD47 effectively depletes host HSCs in immunocompetent mice. In utero depletion of host HSCs increases long-term engraftment after neonatal hematopoietic cell transplantation.

Cover page: Depletion of murine fetal hematopoietic stem cells with c-Kit receptor and CD47 blockade improves neonatal engraftment