Multiferroic coupling has recently been shown to provide an effective and efficient means to transduce energy between various physical regimes and unlike the majority of transduction mechanisms actually improves at reduced length scales. The work presented herein explores the effects of anisotropic energy application to further enhance the coupled behavior of such systems and enable applications such as thermal energy harvesting, electrically small antennas, energy efficient memory, and microscale actuators. Four types of anisotropy are presented: magnetocrystalline, electoelastic, magnetoelastic and shape, which are utilized in joint and competing fashions to deterministically control magnetic and electric states at micro and nanoscales. First, a study is performed to determine the most efficient and energy dense way to trasduce thermal energy into magnetic energy by leveraging single domain magnetic states and the temperature dependence of magentocrystalline anisotropy. A numeric case study is performed which shows that gadolinium and neodymium cobalt are capable of 30% and 22% relative efficiencies, respectively, which is a significant improvement over the state of the art thermoelectric efficiency of 15%. Second, design and testing of an electrically small multiferroic receiver antenna is performed to show the efficient transduction of EM radiation in the HF and VHF frequency spectrums to electrical power in structures which are five orders of magnitude smaller than the wavelength in free-space. A multi-step finite element framework is used to design and simulate an array of magnetostrictive resonator elements which can generate a coherent surface acoustic wave in a piezoelectric substrate. An optimization scheme is used to design systems capable of transmission coefficients on the order of -.4.7 dB. Lastly, a method of directly observing the deterministic control of magnetic states as a function of electric field through the use of Lorentz transmission electron microscopy is presented. Here, magnetoelastic anisotropy is leveraged to reversibly modulate magnetic domain states in a controlled fashion. These results provides significant evidence of the viability of anisotropy enhanced multiferroic transduction to enable future works in energy harvesting, magnetoelectrics and microscale actuators.