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Scholarly Works (1 results)

Article
Peer Reviewed

G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway

Irannejad, Roshanak;
Malik, S;
De, RG;
Trembley, M;
Wedegaertner, PB;
Smrcka, AV

UC San Francisco Previously Published Works (2015)

© 2015 Malik et al.We recently identified a novel GPCR-dependent pathway for regulation of cardiac hypertrophy that depends on Golgi phosphatidylinositol 4-phosphate (PI4P) hydrolysis by a specific isoform of phospholipase C (PLC), PLCε, at the nuclear env