This literature review analyzes different studies and articles that focus on Latina/Hispanic women’s perception of postpartum depression (PPD). The cultural, social, and healthcare delivery barriers Latina/Hispanic women experience and the effect these barriers have on the use of resources are discussed. The following concerns are addressed in more detail: traditional differences, women’s expectations, beliefs about motherhood, the negative stigma around PPD, immigration status, language barriers, and adverse effects of PPD on the infant children of Latina/Hispanic women. Due to cultural factors influencing the underutilization of resources, interventions that target reducing these barriers need to be developed. Further research should be focused on testing the effectiveness of suggested interventions such as implementing universal screening for PPD, having additional support programs available, offering classes about PPD, and involving family members in early informational interventions. The findings of this literature review can be used to help raise awareness about PPD and encourage Latina/Hispanic women struggling with PPD to reach out for help to benefit both themselves and their infants.