Rangers safeguard the balance between humans and nature by protecting and managing biodiversity and natural resources. The challenging working conditions that rangers face make them vulnerable to wildlife attacks and exposure to zoonotic and vector-borne diseases. Despite all of these work-related challenges and threats to their health, a vast majority of rangers lack access to adequate medical treatment facilities. This research has used data from the one of the largest and most comprehensive surveys of rangers across multiple countries, collected as part of the Global Ranger Perception Survey, to examine the relationship between the precarious working conditions of rangers and their health outcomes. By comparing data from the 2020 World Malaria Report, our study highlights the severe malaria burden carried by rangers around the world. Malaria prevalence in rangers working in Central Africa, East Africa, and South America was estimated to be four times higher than in the general population. The results of this study are valuable because they show that rangers are a vulnerable, high-risk population of professionals and their working conditions are highly associated with their respective health outcomes. The research also makes it imperative that improving working conditions is essential for maintaining a professional ranger workforce that protects the planet’s natural areas and biodiversity.