We calculate the gauge terms of the one-loop anomalous dimension matrix for the dimension-six operators of the Standard Model effective field theory (SM EFT). Combining these results with our previous results for the and Yukawa coupling terms completes the calculation of the one-loop anomalous dimension matrix for the dimensionsix operators. There are 1350 CP-even and 1149 CP-odd parameters in the dimensionsix Lagrangian for 3 generations, and our results give the entire 2499 2499 anomalous dimension matrix. We discuss how the renormalization of the dimension-six operators, and the additional renormalization of the dimension d 4 terms of the SM Lagrangian due to dimension-six operators, lays the groundwork for future precision studies of the SM EFT aimed at constraining the effects of new physics through precision measurements at the electroweak scale. As some sample applications, we discuss some aspects of the full RGE improved result for essential processes such as gg h, h and h Z, for Higgs couplings to fermions, for the precision electroweak parameters S and T, and for the operators that modify important processes in precision electroweak phenomenology, such as the three-body Higgs boson decay h Z + and triple gauge boson couplings. We discuss how the renormalization group improved results can be used to study the flavor problem in the SM EFT, and to test the minimal flavor violation (MFV) hypothesis. We briefly discuss the renormalization effects on the dipole coefficient Ce which contributes to e and to the muon and electron magnetic and electric dipole moments. © The Authors.