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Scholarly Works (2 results)

Article
Peer Reviewed

Activating MET kinase rearrangements in melanoma and Spitz tumours

Bastian, Boris;
Leboit, Philip;
Yeh, Iwei;
Botton, T;
Talevich, E;
Shain, AH;
Sparatta, AJ;
De, A;
Mully, TW;
North, JP;
Garrido, MC;
Gagnon, A

UC San Francisco Previously Published Works (2015)

Oncogenic gene fusions have been identified in many cancers and many serve as biomarkers or targets for therapy. Here we identify six different melanocytic tumours with genomic rearrangements of MET fusing the kinase domain of MET in-frame to six different

Article
Peer Reviewed

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

Olshen, Adam;
Bastian, Boris;
Cho, Raymond;
Yeh, Iwei;
Shain, AH;
Garrido, M;
Botton, T;
Talevich, E;
Sanborn, JZ;
Chung, J;
Wang, NJ;
Kakavand, H;
Mann, GJ

UC San Francisco Previously Published Works (2015)

© 2015 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. Desmoplastic melanoma is an uncommon variant of melanoma with sarcomatous histology, distinct clinical behavior and unknown pathogenesis. We performed low-cove