Implementation of quality improvement (QI) initiatives within community mental health settings is crucial to addressing equity-related issues affecting mental health services delivery, including for co-occurring substance use disorders. Given the growing recognition of QI interventions as an effective framework to facilitate structural change within systems of care, it is important to equip mental health providers with the knowledge and ability to execute QI initiatives that are feasible, sustainable, and integrate a health equity lens. To demystify the QI process, we describe the design and methodologies of four fellows' capstone projects conducted during the 2022-2023 academic year at the University of California, San Francisco (UCSF) Public Psychiatry Fellowship at Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG). By highlighting fellows' experiences with leading QI initiatives within community mental health settings, we discuss strategies for overcoming implementation barriers including stakeholder engagement and transparency factors, resource and time constraints, unexpected changes in direction, and lack of infrastructure for QI. Lastly, we reflect on best practices and sustainability considerations for leading QI initiatives in partnership with academic centers, departments of public health, and community mental health clinics.