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Scholarly Works (1 results)

Article
Peer Reviewed

Silencing the transcriptionally active HIV reservoir to improve treatment outcomes.

Prigann, Julia;
Tavora, Rubens;
Furler OBrien, Robert;
Schulze-Gahmen, Ursula;
Boehm, Daniela;
Roan, Nadia;
Nixon, Douglas;
Ndhlovu, Lishomwa;
Valente, Susana;
Ott, Melanie

UC San Francisco Previously Published Works (2024)

Persistence of the transcriptionally active HIV reservoir (TAHR) has important implications for people living with HIV (PLWH), including chronic immune activation and inflammation. Supplementing antiretroviral therapy with HIV transcriptional inhibitors could overcome this by silencing the TAHR.

Cover page: Silencing the transcriptionally active HIV reservoir to improve treatment outcomes.