The discovery of Anti-NMDA Receptor Encephalitis is quite recent, with the first characterization in 2007 by Dr. Josep Dalmau. He noted 12 women who developed acute psychiatric symptoms, seizures, memory deficits, autonomic dysfunction, and decreased level of consciousness often requiring ventilatory support; many cases were associated with presence of a teratoma. In reviewing the current literature of the presentation of Anit-NMDA Receptor Encephalitis in the field of psychiatry, we hope to detail the psychiatric signs and symptoms in order to: standardize the threshold of when to suspect this disease upon presentation of psychosis, when and who to refer the patient to upon suspicion, and how the field of psychiatry can contribute to minimizing the morbidity and mortality of this disease.