- Masson, Carmen L;
- Delucchi, Kevin L;
- McKnight, Courtney;
- Hettema, Jennifer;
- Khalili, Mandana;
- Min, Albert;
- Jordan, Ashly E;
- Pepper, Nicole;
- Hall, Jessica;
- Hengl, Nicholas S;
- Young, Christopher;
- Shopshire, Michael S;
- Manuel, Jennifer K;
- Coffin, Lara;
- Hammer, Hali;
- Shapiro, Bradley;
- Seewald, Randy M;
- Bodenheimer, Henry C;
- Sorensen, James L;
- Des Jarlais, Don C;
- Perlman, David C
Objectives
We evaluated the efficacy of a hepatitis care coordination intervention to improve linkage to hepatitis A virus (HAV) and hepatitis B virus (HBV) vaccination and clinical evaluation of hepatitis C virus (HCV) infection among methadone maintenance patients.Methods
We conducted a randomized controlled trial of 489 participants from methadone maintenance treatment programs in San Francisco, California, and New York City from February 2008 through June 2011. We randomized participants to a control arm (n = 245) and an intervention arm (n = 244), which included on-site screening, motivational-enhanced education and counseling, on-site vaccination, and case management services.Results
Compared with the control group, intervention group participants were significantly more likely (odds ratio [OR] = 41.8; 95% confidence interval [CI] = 19.4, 90.0) to receive their first vaccine dose within 30 days and to receive an HCV evaluation within 6 months (OR = 4.10; 95% CI = 2.35, 7.17). A combined intervention adherence outcome that measured adherence to HAV-HBV vaccination, HCV evaluation, or both strongly favored the intervention group (OR = 8.70; 95% CI = 5.56, 13.61).Conclusions
Hepatitis care coordination was efficacious in increasing adherence to HAV-HBV vaccination and HCV clinical evaluation among methadone patients.