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Scholarly Works (1 results)

Article
Peer Reviewed

Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts

Wu, Chengsheng;
Von Schalscha, Tami;
Sansanwal, Diva;
Qian, Chen;
Jiang, Qinlin;
Shepard, Ryan M;
Wettersten, Hiromi I;
McCormack, Stephen J;
Weis, Sara M;
Cheresh, David A

UC San Diego Previously Published Works (2025)

Significance

Simultaneous targeting of two integrins that function as receptors for FN, a protumor ECM protein, can prevent fibroblasts from supporting the malignant behavior of pancreatic cancer cells.

Cover page: Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts