To be honest, I thought this would be a lost cause.  Even after skipping a New Drugs and Devices essay in 2012, I figured that I would have to search long and hard to find ten new things that emergency practitioners needed to know about.  Although there were no true blockbuster medications for emergency physicians, I nonetheless found ten medicines that we probably should know, along with a new device that may change the way we work up patients with palpitations, and a clever new delivery system for subcutaneous epinephrine. [West J Emerg Med. 2013;14(6):619–628.]