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Open Access Publications from the University of California

Scholarly Works (3 results)

  • Article
Anesthesiology and Pain Medicine (2021)

Electroencephalogram (EEG) monitoring has the potential to become a robust tool to characterize anesthetic depth. The goal is to develop a streamlined neuromonitoring tool that would allow clinicians to make real-time assessments and to titrate anesthetic delivery. Anesthetic overdosing can cause postoperative delirium and mortality, while underdosing can cause intraoperative awareness and pain. Of particular interest is excessively deep anesthesia, which is reflected by a burst suppression pattern on EEG monitors. Fortunately, proprietary algorithms have been developed to transform the raw EEG waveforms into a dimensionless number that quantifies the patient’s level of consciousness. Examples of these monitors are the Bispectral Index (BIS) monitor and the Sedline monitor which produces patient state index (PSI) values.

Question: How do the PSI (SedLine) and BIS perform in the setting of imminent burst suppression during general anesthesia?

    Cover page: Comparison of Depth of Sedation Performance between SedLine and BIS during General Anesthesia: Data Collection and Analysis
    • Article
    • Peer Reviewed
    Dermatology Online Journal, Volume 27, Issue 3 (2021)
      Cover page: Characteristics of patients seen at a dermatology free clinic, 2017-2020: a retrospective chart reviewCreative Commons 'BY-NC-ND' version 4.0 license
      • Article
      Anesthesiology and Pain Medicine (2021)
      The ideal end-tidal concentration of anesthetic dose for a patient under general anesthesia is dynamic and depends on factors. At present, no individual brain function monitoring device has been shown to be substantially superior. Prior studies have attempted to compare the performance of these devices, but a lack of space and common placement locations compromises interpretation. The aim of this protocol is to examine the concordance between processed EEG indices (BIS and PSI) and anesthesia provider assessments across a range of anesthetic depths using a custom engineered interface box.
        Cover page: Comparison of Depth of Sedation Performance between SedLine and BIS during General Anesthesia: Background and Protocol Development
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