The Internet of Things (IoT) is a growing network of heterogeneous devices, combining various sensing and computing nodes at different scales, which creates a large volume of data. Many IoT applications use machine learning (ML) algorithms to analyze the data. The high computational complexity of ML workloads poses significant computational challenges to IoT computing platforms, which tend to be less-powerful and resource-constrained devices. Transmitting such large volumes of data to the cloud also have various issues such as scalability, security and privacy. In this dissertation, we propose efficient solutions to perform the ML tasks while decreasing power consumption and improving performance. We first leverage the heterogeneous and interconnected nature of the IoT systems, where IoT applications run on many different architectures (e.g., X86 server or ARM-based edge device) while communicating with each other. We present a cross-platform power and performance prediction technique for intelligent task allocation. The proposed technique estimates the time-variant energy consumption with only 7% error across completely different architectures, enabling the intelligent task allocation that saves the energy consumption of 16.5% for state-of-the-art ML workloads.

We next show how to further advance the learning procedures towards real-time and online processing by distributing such learning tasks onto the hierarchy of IoT devices. Our solution leverages brain-inspired high-dimensional (HD) computing to derive a new class of

learning algorithms that can easily run on IoT devices, while providing high accuracy comparable to the state-of-the-arts. We present that the HD-based learning algorithms can cover various real-world problems from conventional classification to other cognitive tasks beyond classical MLs such as DNA pattern matching. We demonstrate that the HD-based learning can enable secure, collaborative learning by efficiently distributing a large volume of learning tasks into heterogeneous computing nodes. We have implemented the proposed learning solution on various platforms while offering superior computing efficiency. For example, our solution achieves 486×

and 7× performance improvements for each of the training and inference phases on a low-power ARM processor, as compared to state-of-the-art deep learning.