Developing the final summative assessment of a course at the start of curriculum development is an implementation of “backward design,” whereby learning objectives are identified first and the curriculum is engineered end-to-beginning to achieve them. We trained in backward design through the Professional Development Program (PDP) and adapted PDP assessment ideas for evaluation of curriculum designs and teaching efficacy. A pre‑/post-quiz is an assessment administered the first and last day of a course; a learner’s scores are used to measure normalized gain: the ratio of what a student learned during a course relative to what they knew entering it. The intentional process of developing a pre‑/post-quiz for every course focuses the educator on the essential understanding desired of the learners exiting the course. The normalized-gain statistics for the course can then be used to evaluate the course’s efficacy, and improvements to the curriculum can be monitored by tracking the normalized gains over time, using the same pre‑/post-quiz. Moreover, an individual instructor may self-evaluate their teaching efficacy by tracking normalized gains from all courses over time. Here we discuss applying the practice of backward curriculum design starting with a custom pre‑/post-quiz and utilizing it for immediate and longitudinal evaluation, focusing primarily on designing an entire undergraduate science course.