Certain mammals and birds may damage or destroy southern pines, causing economic losses in intensively cultured areas such as seed orchards and nurseries. Mammal pests may eat seeds; tunnel, dislodging seedlings, or chew on roots; or girdle, debark, or sever stems or branches. Bird pests may eat seeds or excavate holes in the tree trunks. The first important step is to identify the pest(s) from the damage left behind. Thereafter, various control options−from using traps and repellents to altering habitat−are available.

Quelea quelea and some other species of weaverbirds (Ploceidae) cause severe damage to cereal crops in sahelian zones of Africa. Recent observations of weaverbird damage to cereals in the Lake Chad Basin show that crops grown in certain places at particular times are more likely to be damaged than others. Timing of harvest by varying planting times and selection of short-cycle cereals may avoid damage in some situations.

Avicidal sprays are likely to continue to be a major tool in controlling Quelea quelea nesting colonies when they are found in cereal producing areas. New observations on nesting behavior indicate that a single parent cannot successfully care for the nest if the other parent is destroyed before the eggs have hatched. During the incubation period, Quelea return earlier in the evening and males are more concentrated in night roosting areas than after the eggs have hatched. These factors indicate that for the most efficient control, the best time to spray nesting colonies is before hatching begins.

The general public in the state of Georgia is faced with at least 45 kinds of vertebrate animal damage control problems. Their questions asking for problem solutions are often directed to Georgia Cooperative Extension Service agents in 156 counties. County agents in the Atlanta Metropolitan Area receive an average of 325 requests for vertebrate pest control information a year. Agents in the Coastal Plain Area receive an average of 140 questions per year as does the Extension Wildlife Specialist. The combined total of vertebrate animal damage control questions received by all agents is approximately 60,000 per year. Typically difficult questions are referred to the wildlife specialist while common questions are handled by local agents. The most frequent requests concern problems in homes, other structures, and yards. Requests concerning agricultural losses in gardens and on farms ranked next. Requests to solve predator damage problems ranked last. Extension information is very effective when applied to problems with simple solutions. Vertebrate pest problems with complex solutions usually need the direct involvement of a specialist to be effectively solved.

The asymmetric synthesis of dragmacidin D (1) was completed in 10 steps. Its sole stereocenter was set by using direct asymmetric alkylation enabled by a C2-symmetric tetramine and lithium N-(trimethylsilyl)-tert-butylamide as the enolization reagent. A central Larock indole synthesis was employed in a convergent assembly of the heterocyclic subunits. The stereochemical evidence from this work strongly supports the predicted S configuration at the 6''' position, which is consistent with other members of the dragmacidin family of natural products.

The scalable synthesis of the oxaquinolizidine marine natural product desmethylxestospongin B is based on the early application of Ireland-Claisen rearrangement, macrolactamization, and a late-stage installation of the oxaquinolizidine units by lactam reduction. The synthesis serves as the source of material to investigate calcium signaling and its effect on mitochondrial metabolism in various cell types, including cancer cells.

Lithium enolates derived from carboxylic acids are ubiquitous intermediates in organic synthesis. Asymmetric transformations with these intermediates, a central goal of organic synthesis, are typically carried out with covalently attached chiral auxiliaries. An alternative approach is to utilize chiral reagents that form discrete, well-defined aggregates with lithium enolates, providing a chiral environment conducive of asymmetric bond formation. These reagents effectively act as noncovalent, or traceless, chiral auxiliaries. Lithium amides are an obvious choice for such reagents as they are known to form mixed aggregates with lithium enolates. We demonstrate here that mixed aggregates can effect highly enantioselective transformations of lithium enolates in several classes of reactions, most notably in transformations forming tetrasubstituted and quaternary carbon centers. Easy recovery of the chiral reagent by aqueous extraction is another practical advantage of this one-step protocol. Crystallographic, spectroscopic, and computational studies of the central reactive aggregate, which provide insight into the origins of selectivity, are also reported.