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Scholarly Works (2 results)

Article
Peer Reviewed

Transcriptional Regulation of Apolipoprotein A5 Gene Expression by theNuclear Receptor ROR alpha

Genoux, Annelise;
Dehondt, Helene;
Helleboid-Chapman, Audrey;
Duhem, Christian;
Hum, Dean W.;
Martin, Genevieve;
Pennacchio, Len;
Staels, Bart;
Fruchart-Najib, Jamila;
Fruchart, Jean-Charles

Lawrence Berkeley National Laboratory (2004)

Apolipoprotein A5 has recently been identified as a crucial determinant of plasma triglyceride levels. Our results showed that RORa up-regulates human APOA5 but has no effect on mouse apoa5 promoter. These data suggest an additional important physiological role for RORa in the regulation of genes involved in plasma triglyceride homeostasis in human and probably in the development of atherosclerosis

Cover page: Transcriptional Regulation of Apolipoprotein A5 Gene Expression by theNuclear Receptor ROR
alpha

Article
Peer Reviewed

Impact of age on NIS2+™ and other non-invasive blood tests for the evaluation of liver disease and detection of at-risk MASH

Anstee, Quentin M;
Magnanensi, Jeremy;
Hajji, Yacine;
Caron, Alexandra;
Majd, Zouher;
Rosenquist, Christian;
Hum, Dean W;
Staels, Bart;
Connelly, Margery A;
Loomba, Rohit;
Harrison, Stephen A;
Ratziu, Vlad;
Sanyal, Arun J

UC San Diego Previously Published Works (2024)