Search

Scholarly Works (1 results)

Article
Peer Reviewed

Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antivirals.

Lingappa, Vishwanath;
Broce, S;
Hensley, L;
Sato, T;
Lehrer-Graiwer, J;
Essrich, C;
Edwards, KJ;
Pajda, J;
Davis, CJ;
Bhadresh, R;
Hurt, CR

UC San Francisco Previously Published Works (2016)

Viral capsid assembly involves the oligomerization of the capsid nucleoprotein (NP), which is an essential step in viral replication and may represent a potential antiviral target. An in vitro transcription-translation reaction using a wheat germ (WG) extr