Although community partners in participatory research need to understand basic principles of research ethics and human subjects protections, few tools have been designed with these partners in mind. To assist in this process, and help engage youth community partners in learning this critical material, a game was developed based on the popular television program Jeopardy(TM). Piloted with a group of 18 Mexican- American adolescents as part of a broader community-based participatory research(CBPR) project, the game begins with small group study of infamous cases of research ethics violations (eg. the Tuskegee Syphilis Study) and of the human subjects protections that resulted. The participants then play the Jeopardy game in teams, responding to “What is . . . ?” questions concerning the five infamous research studies and corresponding human subjects protections. Although observational findings revealed substantial learning and active engagement in the process, as well as strong retention of the material several months later, the tool requires further evaluation. Based on this pilot experience, however, we believe the Research Ethics Jeopardy™ Game offers promise in helping youth and other community partners in CBPR master critical information about human subjects protections and their importance in an accessible and lively manner.